The overall goal of my research is to improve the outcomes of patients with cardiac disease. Within this overall goal, I have particularly focused on translation cardiovascular devices from bench to bedside practice. My research work includes but is not limited heart failure, cell therapy, cardiovascular implantable devices, vascular imaging, invasive and non-invasive coronary physiology, endothelial function evaluation, vascular healing response to implanted devices, and structure heart devices. I have 10 issued and 2 provisional U.S. patents. By leading and managing numbers of preclinical studies, I mentored & supervised more than 20 individuals including senior Georgia tech students, hospital residents, the 1st year of interventional cardiology fellows, as well as oversee interventional cardiologists. I have number of invited lectures from cardiology conferences in China, as well as served as peer reviewer for numbers of journals, and a reviewer for AHA grant and several cardiology conferences. I published more than 200 scientific manuscripts, reviews and abstracts.