Treatment of Coronary Bifurcation Lesions: Comparing Reverse T and Protrusion Versus Double-kissing and Crush Stenting (TIPTAP-I)

Treatment of bifurcation coronary lesions may be challenging, and the best technique to be used in these settings remains to be established. While a single stent strategy is simpler and has been often encouraged, a number of studies show that the use of modern stent implantation techniques may bring some advantages in terms of target lesion failure during longer follow-up. Further, single-stent procedures are not possible at all in some settings, for instance when both main and side branch have similar diameters and present both relevant disease, particularly when the angle between the vessels is lower than 70°. Recent randomized data demonstrate the superiority of DK-Crush technique over provisional stenting, however, DK-Crush is cumbersome, time-consuming and requires very experienced operators. The investigators therefore plan to undertake a randomized study comparing a novel interventional technique against DK-crush in the setting of true bifurcation lesions (Medina lesions type 1,1,1 or 0,1,1). 50 participants, Germany.

ClinicalTrials.gov Identifier: NCT03714750

Trial registry on clinicaltrials.gov

Other Specialist Resources for Bifurcation Club

Including recently published studies, coverage of late-breaking science, updates from clinical trials and registries, and complex case presentations.

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Complex LCx CTO Bifurcation Intervention

50-year-old male with extensive CAD presented with progressive CCS Class II angina and high risk SPECT MPI for multivessel is...

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