Emmanouil S. Brilakis, MD, PhD, is Director of the Center for Complex Coronary Interventions at the Minneapolis Heart Institute and Chairman of the Center for Coronary Artery Disease at the Minneapolis Heart Institute Foundation.  

After graduating from Lycee Leonin de Patissia, Dr. Brilakis received his medical degree from the National Kapodistrian University of Athens, Greece. He trained in internal medicine, cardiovascular diseases, and interventional cardiology at the Mayo Clinic. He also completed a Master's in clinical research at the Mayo Clinic and a PhD in clinical research at the National Kapodistrian University of Athens, Greece. He served as director of the cardiac catheterization laboratories at VA North Texas Health Care System from 2004-2016. He was on the faculty of the University of Texas Southwestern Medical School from 2004 to 2018.  

Dr. Brilakis leads a large clinical trial and education group investigating treatment of chronic total occlusions and other complex coronary lesions such as bifurcations, heavy calcification, and saphenous vein grafts, prevention and management of complications, coronary imaging, radiation safety in the catheterization laboratory, physician wellbeing, and implementation of AI and novel technologies in healthcare.  

Dr. Brilakis has authored or co-authored over 1,000 manuscripts and has written the Manual of Percutaneous Coronary Interventions and the Manual of CTO Interventions, now in its 3rd edition. He created the Manual of CTO Interventions and the Manual of PCI YouTube series and websites. He is on the Board of the Cardiovascular Innovations Foundation, an associate editor for Circulation, a section editor for Eurointervention, and an editorial board member and reviewer for several journals and grant agencies.