Clinical Documents Position Statement icon

SCAI Position Statement on Optimal Interventional Therapy for Complex Coronary Artery Disease

Position Statement Physiology

While the terms “complex CAD” or “high‐risk CAD” have not been formally defined, they encompass both complex anatomic lesions and clinical parameters including advanced age, frailty, comorbidities, compromised hemodynamic status, depressed ventricular function and concomitant valvular disease. Such features increase both the procedural complexity of percutaneous coronary intervention (PCI) and the risk of adverse patient outcomes. This statement aims to:

  • Present state‐of‐the art clinical evidence regarding PCI in patients with complex clinical and anatomical features
  • Provide procedural guidance to achieve optimal outcomes for this challenging patient group
PCI Risk Stratification pyramid
18.2 million

Americans with coronary artery disease

All authors: Robert F. Riley, MD, MS, FSCAI; Timothy D. Henry, MD, MSCAI; Ehtisham Mahmud, MD, MSCAI; Ajay J. Kirtane, MD, SM, FSCAI; Emmanouil S. Brilakis MD, PhD, FSCAI, Abhinav Goyal, MD; Cindy L. Grines, MD, MSCAI; William L. Lombardi, MD, FSCAI; Anbukarasi Maran, MD, FSCAI; Tanveer Rab, MD, FSCAI; Jennifer A. Tremmel, MD, MS, FSCAI; Alexander G. Truesdell, MD, FSCAI; Robert W. Yeh, MD, MSc, MBA, FSCAI; David X. Zhao, MD, FSCAI; and Farouc A. Jaffer, MD, PhD, FSCAI.

Other Guidance Documents

Evidence-based recommendations that promote optimal patient care based on current state-of-the-art science in interventional cardiology.